I'm not even gonna deny it or anything: my favorite thing about this adaptation of Osamu Tezuka's manga is Kou Shibasaki's fantastic performance as the title character, a funny little thief who talks and acts like a tough guy (in the manga, Dororo was a boy) and has mud on her face all the time. I freely admit to being totally moemoe for her.
That said, I was surprised by just how good this movie was! Dororo is a big-budget and beautifully-made adaptation of the sort I wasn't really ready for when I sat down in the theater. My eyes were quite pleasantly shocked by a visual style that's hard to describe. Not a Tezuka comic brought to life, but a place somewhere in between: a colorful but not saccharine reality populated, occassionally, by CG monsters that do in fact look like they stepped off the comic page. I've never read Dororo (Vertical is putting it out soon!), but as soon as you see these guys, if you know Tezuka, you'll stop and say "Ah, now that's Tezuka." You could certainly argue that they clash-- particularly during a rubber-suit fight that I loved more than all the others put together-- but I think that in a very surreal way, they mesh.
Dororo is about a young man by the name of Hyakkimaru, whose body was sacrificed to demons in 48 parts by his father before birth. Baby Hyakkimaru was found, had replacement parts fitted to him (suspend your disbelief already!), and grew up to search for the parts he lost by killing the demons who hold them. At the beginning of the movie, he's joined by Dororo, who we've talked about. The movie deals with family realtionships throughout and climaxes with a conflicted Hyakkimaru finding and fighting the father who betrayed him.
Overall, I would say that Dororo is the best movie I watched this weekend. I can't find a single flaw with it: everything it sets out to do, it does just right. The fantasy world is gorgeously realized, the action is top-notch, and the emotion is genuine. Learning that this is the first of a planned trilogy was the best news I've had all week.